It has been a privilege to have recently been involved in an exciting new collaboration with Alexander Tropsha and Denis Fourches at the University of North Carolina. The team carried out a cheminformatics analysis of the assertional metadata (AMD) from BioWisdom’s Safety Intelligence Program (SIP), the world’s largest, ever-expanding collection of the known effects of drugs and other chemicals. SIP makes use of BioWisdom’s collection of key concept metadata and Sofia technology, which translates the varied and diverse language used by scientists into a semantically consistent form. The study has provided a fresh new perspective on historic public domain data, bringing together isolated fragments of toxicology information, spanning decades, to provide new insight into drug safety. The resulting article, entitled “Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species”, was published in Chemical Research in Toxicology on December 16, 2009.

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19^TH January 2010 Cambridge, UK – BioWisdom. a provider of specialist medical metadata and Intelligence Solutions for Healthcare, is pleased to announce the publication of an exciting new paper in Chem. Res. Toxicol. Using metadata derived from BioWisdom’s Safety Intelligence Program, Alex Tropsha and colleagues at the University of North Carolina have applied QSAR modelling and other chemoinformatics techniques to qualitative assertions abstracted from legacy data.

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