An unparalleled resource for drug safety
The Safety Intelligence System represents the largest forever-expanding collection of known effects of chemicals occurring in the different tissue, drugs effects on clinical biomarkers of tissue injury and drug molecular mechanisms.
The System currently contains almost 100,000 individual ‘facts' assertions relating to the liver responses, affected by over 5,500 different compounds in over 20 different species. These assertions distill the observations and conclusions made across more than 19 million documents and database records, including regulatory documents, drug labels, pre-clinical and clinical research journals.
Using our intelligent search technology, we automatically ‘read' millions of documents and store key observations as ‘assertional meta-data'. This meta-data is stored in a semantically consistent format which dramatically improves the pace and efficiency of analysis. Although millions of documents are read automatically, a task which would take hundreds of highly trained experts many months to achieve, we are able with rigorous quality control by PhD level scientists to deliver over 97% accuracy.
Members Forum: A Global community
|
|
The Members Forum gives you the opportunity to interact with a rapidly expanding community of scientists (clinical or preclinical; chemist or biologists) all with a common interest in using the Safety Intelligence System to improve our understanding of mechanisms of drug-related adverse events. All Members have access to a series of large scale assertional meta-data analyses performed by us or other members and the opportunity to participate in a series of Webinars or other forms of interaction with other scientists. This creates the opportunity to learn from others about their applications of the Safety Intelligence System and the ever growing collection of assertional meta-data. Log-in to the SIP membership forum (members only) |
Coming soon....
The content of the Safety Intelligence System is expanding daily. In the next three months, we will expand the assertional meta-data in the System to other tissues, starting with the cardiac system, followed by kidney. The list of data sources used is also expanding, we are currently working on the FDA New Drug Applications for liver effects - this will also be available in the next 3 months. The content grows according to the sponsorship of our Charter Members. As a Charter Member, you prioritise what is created built and when; in return Charter Members receive perpetual rights to the data.
An intuitive search interface
The Safety Intelligence System is accessible using an internet explorer from anywhere in the world.
As well as the usual 'quick search' box for keyword searching, the system allows searching by chemical structure. Advanced 'assertional meta-data' searching is also possible, for example, you can search for all compounds causing liver necrosis in seconds. Our unique format of ‘assertional meta-data' allows you to complex analyses to be performed.
Any search can be saved as a favourite to speed up future searching and the system has in-built alerting functionality so you will be automatically notified of any changes in the data that impact a saved query.
Click here to view demonstrations of the system.
Join Now
Click here for membership options. Alternatively, email sip@biowisdom.com for more information or if you would prefer to contact us directly, please call our telephone sales department, United Kingdom +44 (0)1223 874838, United States toll free +1 866 466 6484. Our telephone sales are open during normal office hours 09:00 to 17:30, Monday through Friday.
SIP Webinar Series
To view the webinar, you will need Windows Media Player installed on your system. Click here to download.
Date |
Title |
Register |
View
|
View
|
|
23 October 2008 |
Understanding Hepatobiliary Transport Inhibition |
Expired |
|
|
|
19 November 2008 |
Chemoinformatics Analysis of Assertions describing Drug-Induced Liver Injury |
|
|
|
|
|
AstraZeneca's experience in the Safety Intelligence Program: Learning from history to avoid idiot-syncracy |
Expired |
|
|
|
11 February 2009 |
The Safety Intelligence Program: Supporting Discovery, Regulatory and Pharmacovigilance. Current strengths and future directions. |
Expired |
|
|
